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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734300
Species: Mus musculus
RGD Object: Gene
Symbol: Bcl2l11
Name: BCL2 like 11
Acc ID: CHEBI:50131
Term: 5-aza-2'-deoxycytidine
Definition: A 2'-deoxyribonucleoside that has formula C8H12N4O4.
Chemical ID: MESH:C014347
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2l11decreases methylationISOBCL2L11 (Homo sapiens)6480464CTDDecitabine results in decreased methylation of BCL2L11 promoterPMID:19403302
Bcl2l11increases expressionISOBCL2L11 (Homo sapiens)6480464CTDDecitabine results in increased expression of BCL2L11 mRNA; Decitabine results in increased expression of BCL2L11 proteinPMID:19403302
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