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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732397
Species: Mus musculus
RGD Object: Gene
Symbol: Jup
Name: junction plakoglobin
Acc ID: CHEBI:50131
Term: 5-aza-2'-deoxycytidine
Definition: A 2'-deoxyribonucleoside that has formula C8H12N4O4.
Chemical ID: MESH:C014347
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Jupincreases expressionISOJUP (Homo sapiens)6480464CTDDecitabine results in increased expression of JUP mRNA; Decitabine results in increased expression of JUP proteinPMID:16887905 PMID:18974268
Jupmultiple interactionsISOJUP (Homo sapiens)6480464CTDDNMT3A protein affects the reaction [Decitabine results in increased expression of JUP mRNA]; DNMT3B protein affects the reaction [Decitabine results in increased expression of JUP protein]PMID:16887905
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