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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731911
Species: Mus musculus
RGD Object: Gene
Symbol: Mmp9
Name: matrix metallopeptidase 9
Acc ID: CHEBI:50131
Term: 5-aza-2'-deoxycytidine
Definition: A 2'-deoxyribonucleoside that has formula C8H12N4O4.
Chemical ID: MESH:C014347
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp9increases expressionEXP 6480464CTDDecitabine results in increased expression of MMP9 mRNAPMID:27915011
Mmp9multiple interactionsEXP 6480464CTDDecitabine inhibits the reaction [[bisphenol A affects the susceptibility to [Lipopolysaccharides co-treated with IFNG protein]] which results in decreased expression of MMP9 mRNA]PMID:29718165
Mmp9decreases expressionISOMMP9 (Homo sapiens)6480464CTDDecitabine results in decreased expression of MMP9 proteinPMID:29320940
Mmp9multiple interactionsISOMMP9 (Homo sapiens)6480464CTDDecitabine inhibits the reaction [sodium arsenite results in increased expression of MMP9 mRNA]; Decitabine inhibits the reaction [sodium arsenite results in increased expression of MMP9 protein]PMID:21167264
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