Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730893
Species: Mus musculus
RGD Object: Gene
Symbol: Nfkb1
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
Acc ID: CHEBI:50131
Term: 5-aza-2'-deoxycytidine
Definition: A 2'-deoxyribonucleoside that has formula C8H12N4O4.
Chemical ID: MESH:C014347
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfkb1decreases expressionEXP 6480464CTDDecitabine results in decreased expression of NFKB1 mRNAPMID:27915011
Nfkb1affects expressionISONFKB1 (Homo sapiens)6480464CTDDecitabine affects the expression of NFKB1 mRNAPMID:23300844
Nfkb1increases expressionISONFKB1 (Homo sapiens)6480464CTDDecitabine results in increased expression of NFKB1 mRNA; Decitabine results in increased expression of NFKB1 proteinPMID:19027835
Nfkb1multiple interactionsISONFKB1 (Homo sapiens)6480464CTDDecitabine promotes the reaction [NFKB1 protein binds to IER3 promoter]; TNF protein promotes the reaction [Decitabine promotes the reaction [NFKB1 protein binds to IER3 promoter]]PMID:19117987
Go Back to source page   Continue to Ontology report