GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nfkb1 | affects expression | ISO | NFKB1 (Homo sapiens) | 6480464 | CTD | Decitabine affects the expression of NFKB1 mRNA | PMID:23300844 | Nfkb1 | decreases expression | ISO | Nfkb1 (Mus musculus) | 6480464 | CTD | Decitabine results in decreased expression of NFKB1 mRNA | PMID:27915011 | Nfkb1 | increases expression | ISO | NFKB1 (Homo sapiens) | 6480464 | CTD | Decitabine results in increased expression of NFKB1 mRNA; Decitabine results in increased expression of NFKB1 protein | PMID:19027835 | Nfkb1 | multiple interactions | ISO | NFKB1 (Homo sapiens) | 6480464 | CTD | Decitabine promotes the reaction [NFKB1 protein binds to IER3 promoter]; TNF protein promotes the reaction [Decitabine promotes the reaction [NFKB1 protein binds to IER3 promoter]] | PMID:19117987 | | ||||||||||||||||||||||
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