GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CLDN3 | increases expression | EXP | | 6480464 | CTD | Decitabine results in increased expression of CLDN3 mRNA; Decitabine results in increased expression of CLDN3 protein | PMID:16367923 PMID:17986852 | CLDN3 | multiple interactions | EXP | | 6480464 | CTD | [Decitabine co-treated with trichostatin A] inhibits the reaction [MBD2 protein binds to CLDN3 promoter]; [Decitabine co-treated with trichostatin A] promotes the reaction [SP1 protein binds to CLDN3 promoter]; [Decitabine co-treated with trichostatin A] promotes the reaction [SP3 protein binds to CLDN3 promoter]; Decitabine inhibits the reaction [MBD2 protein binds to CLDN3 promoter]; Decitabine promotes the reaction [SP1 protein binds to CLDN3 promoter]; Decitabine promotes the reaction [SP3 protein binds to CLDN3 promoter]; trichostatin A promotes the reaction [Decitabine results in increased expression of CLDN3 mRNA]; trichostatin A promotes the reaction [Decitabine results in increased expression of CLDN3 protein] | PMID:17986852 | | ||||||||||||||||||||||
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