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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 6497694
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hmgn5
Name: high mobility group nucleosome binding domain 5
Acc ID: CHEBI:50131
Term: 5-aza-2'-deoxycytidine
Definition: A 2'-deoxyribonucleoside that has formula C8H12N4O4.
Chemical ID: MESH:C014347
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hmgn5decreases methylationEXP 6480464CTDDecitabine results in decreased methylation of HMGN5 promoterPMID:22109888
Hmgn5multiple interactionsEXP 6480464CTD[Decitabine results in decreased methylation of HMGN5 promoter] which results in increased expression of HMGN5 mRNAPMID:22109888
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