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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1551432
Species: Mus musculus
RGD Object: Gene
Symbol: Oprm1
Name: opioid receptor, mu 1
Acc ID: CHEBI:50131
Term: 5-aza-2'-deoxycytidine
Definition: A 2'-deoxyribonucleoside that has formula C8H12N4O4.
Chemical ID: MESH:C014347
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Oprm1affects methylationEXP 6480464CTDDecitabine affects the methylation of OPRM1 promoterPMID:17452465
Oprm1multiple interactionsEXP 6480464CTD[Decitabine affects the methylation of OPRM1 promoter] which affects the expression of OPRM1 mRNAPMID:17452465
Oprm1increases expressionISOOPRM1 (Homo sapiens)6480464CTDDecitabine results in increased expression of OPRM1 mRNAPMID:22262103
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