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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1346183
Species: Homo sapiens
RGD Object: Gene
Symbol: BID
Name: BH3 interacting domain death agonist
Acc ID: CHEBI:50131
Term: 5-aza-2'-deoxycytidine
Definition: A 2'-deoxyribonucleoside that has formula C8H12N4O4.
Chemical ID: MESH:C014347
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BIDaffects expressionEXP 6480464CTDDecitabine affects the expression of BID mRNAPMID:23300844
BIDmultiple interactionsEXP 6480464CTD[Valproic Acid co-treated with Decitabine] results in increased cleavage of BID proteinPMID:21771726
BIDdecreases methylationISOBid (Mus musculus)6480464CTDDecitabine results in decreased methylation of BID genePMID:27923600
BIDincreases expressionISOBid (Mus musculus)6480464CTDDecitabine results in increased expression of BID mRNAPMID:27915011
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