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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307800
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Apobec3
Name: apolipoprotein B mRNA editing enzyme catalytic subunit 3
Acc ID: CHEBI:50131
Term: 5-aza-2'-deoxycytidine
Definition: A 2'-deoxyribonucleoside that has formula C8H12N4O4.
Chemical ID: MESH:C014347
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Apobec3multiple interactionsISOApobec3 (Mus musculus)6480464CTD[pyrimidin-2-one beta-ribofuranoside results in decreased activity of APOBEC3B protein] which results in increased susceptibility to Decitabine; pyrimidin-2-one beta-ribofuranoside inhibits the reaction [APOBEC3B protein results in decreased amination of Decitabine]PMID:18398609
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