GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Atr | affects localization | ISO | ATR (Homo sapiens) | 6480464 | CTD | Decitabine affects the localization of ATR protein modified form | PMID:17991895 | Atr | decreases expression | ISO | Atr (Mus musculus) | 6480464 | CTD | Decitabine results in decreased expression of ATR mRNA | PMID:27915011 | Atr | increases activity | ISO | ATR (Homo sapiens) | 6480464 | CTD | Decitabine results in increased activity of ATR protein | PMID:17977830 | Atr | multiple interactions | ISO | ATR (Homo sapiens) | 6480464 | CTD | ATR protein affects the reaction [Decitabine results in increased expression of TP53 protein]; Decitabine promotes the reaction [ATR protein results in increased phosphorylation of TP53 protein]; RPA1 protein affects the reaction [Decitabine results in increased activity of ATR protein] | PMID:17977830 | | ||||||||||||||||||||||
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