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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10596
Species: Mus musculus
RGD Object: Gene
Symbol: Fos
Name: FBJ osteosarcoma oncogene
Acc ID: CHEBI:50131
Term: 5-aza-2'-deoxycytidine
Definition: A 2'-deoxyribonucleoside that has formula C8H12N4O4.
Chemical ID: MESH:C014347
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fosaffects expressionISOFOS (Homo sapiens)6480464CTDDecitabine affects the expression of FOS mRNAPMID:17145863
Fosmultiple interactionsISOFos (Rattus norvegicus)6480464CTDDecitabine inhibits the reaction [FOS protein results in decreased susceptibility to Cisplatin]; Decitabine inhibits the reaction [FOS protein results in decreased susceptibility to Hydrogen Peroxide]PMID:18314485
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