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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621758
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp12
Name: caspase 12
Acc ID: CHEBI:50103
Term: excitatory amino acid agonist
Definition: An agent that binds to and activates excitatory amino acid receptors.
Chemical ID: MESH:D018690
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7314426480464CTDExcitatory Amino Acid Agonists results in increased expression of and results in increased cleavage of CASP12 protein, Plant Extracts inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of and results in increased cleavage of CASP12 protein]

PMID:28315776
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.