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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62109
Species: Mus musculus
RGD Object: Gene
Symbol: Col1a1
Name: collagen, type I, alpha 1
Acc ID: CHEBI:50103
Term: excitatory amino acid agonist
Definition: An agent that binds to and activates excitatory amino acid receptors.
Chemical ID: MESH:D018690
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Col1a1increases expressionISOCOL1A1 (Homo sapiens)6480464CTDExcitatory Amino Acid Agonists results in increased expression of COL1A1 mRNAPMID:28987794
Col1a1multiple interactionsISOCOL1A1 (Homo sapiens)6480464CTDDizocilpine Maleate inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of COL1A1 mRNA]; Excitatory Amino Acid Antagonists inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of COL1A1 mRNA]; U 0126 inhibits the reaction [Excitatory Amino Acid Agonists results in increased expression of COL1A1 mRNA]PMID:28987794
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