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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2202
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bdnf
Name: brain-derived neurotrophic factor
Acc ID: CHEBI:50103
Term: excitatory amino acid agonist
Definition: An agent that binds to and activates excitatory amino acid receptors.
Chemical ID: MESH:D018690
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bdnfdecreases expressionEXP 6480464CTDExcitatory Amino Acid Agonists results in decreased expression of BDNF mRNAPMID:29425760
Bdnfmultiple interactionsEXP 6480464CTDagathisflavone inhibits the reaction [Excitatory Amino Acid Agonists results in decreased expression of BDNF mRNA]; Estradiol inhibits the reaction [Excitatory Amino Acid Agonists results in decreased expression of BDNF mRNA]PMID:29425760
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