GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CCND1 | increases expression | ISO | Ccnd1 (Rattus norvegicus) | 6480464 | CTD | Methylnitrosourea results in increased expression of CCND1 protein | PMID:18155124 | CCND1 | multiple interactions | ISO | Ccnd1 (Rattus norvegicus) | 6480464 | CTD | [Methylnitrosourea co-treated with Estradiol] results in increased expression of CCND1 mRNA; [Methylnitrosourea co-treated with Estradiol] results in increased expression of CCND1 protein; [Methylnitrosourea co-treated with Progesterone co-treated with Estradiol] results in increased expression of CCND1 mRNA; [Methylnitrosourea co-treated with Progesterone co-treated with Estradiol] results in increased expression of CCND1 protein; [Methylnitrosourea co-treated with Progesterone] results in increased expression of CCND1 mRNA; [Methylnitrosourea co-treated with Progesterone] results in increased expression of CCND1 protein; [Methylnitrosourea co-treated with Testosterone] results in increased expression of CCND1 protein; Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in increased expression of CCND1 protein] | PMID:20732338 PMID:25164625 | | ||||||||||||||||||||||
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