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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620307
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pdpk1
Name: 3-phosphoinositide dependent protein kinase-1
Acc ID: CHEBI:50102
Term: N-methyl-N-nitrosourea
Definition: A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by methyl and nitroso groups.
Chemical ID: MESH:D008770
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pdpk1multiple interactionsEXP 6480464CTD[Methylnitrosourea co-treated with Testosterone] results in increased phosphorylation of PDPK1 protein; Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in increased phosphorylation of PDPK1 protein]PMID:25164625
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