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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306069
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vrk1
Name: VRK serine/threonine kinase 1
Acc ID: CHEBI:50102
Term: N-methyl-N-nitrosourea
Definition: A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by methyl and nitroso groups.
Chemical ID: MESH:D008770
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vrk1decreases expressionISOVRK1 (Homo sapiens)6480464CTDMethylnitrosourea results in decreased expression of VRK1 proteinPMID:27233451
Vrk1multiple interactionsISOVRK1 (Homo sapiens)6480464CTDTP53 protein promotes the reaction [Methylnitrosourea results in decreased expression of VRK1 protein]PMID:27233451
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