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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733990
Species: Homo sapiens
RGD Object: Gene
Symbol: ACAA2
Name: acetyl-CoA acyltransferase 2
Acc ID: CHEBI:5001
Term: fenofibrate
Definition: A chlorobenzophenone that is (4-chlorophenyl)(phenyl)methanone substituted by a [2-methyl-1-oxo-1-(propan-2-yloxy)propan-2-yl]oxy group at position 1 on the phenyl ring.
Chemical ID: MESH:D011345
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ACAA2increases expressionEXP 6480464CTDFenofibrate results in increased expression of ACAA2 mRNAPMID:25572481
ACAA2affects expressionISOAcaa2 (Rattus norvegicus)6480464CTDFenofibrate affects the expression of ACAA2 mRNAPMID:20801182
ACAA2increases expressionISOAcaa2 (Rattus norvegicus)6480464CTDFenofibrate results in increased expression of ACAA2 mRNA; Fenofibrate results in increased expression of ACAA2 proteinPMID:20118634 PMID:27665778 PMID:32741897
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