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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2397
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cpt1b
Name: carnitine palmitoyltransferase 1B
Acc ID: CHEBI:5001
Term: fenofibrate
Definition: A chlorobenzophenone that is (4-chlorophenyl)(phenyl)methanone substituted by a [2-methyl-1-oxo-1-(propan-2-yloxy)propan-2-yl]oxy group at position 1 on the phenyl ring.
Chemical ID: MESH:D011345
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cpt1baffects expressionEXP 6480464CTDFenofibrate affects the expression of CPT1B mRNAPMID:20801182
Cpt1bincreases expressionEXP 6480464CTDFenofibrate results in increased expression of CPT1B mRNAPMID:16595124 PMID:19395589 PMID:27071702 PMID:32741897
Cpt1bmultiple interactionsEXP 6480464CTDFenofibrate inhibits the reaction [Pyrazinamide results in decreased expression of CPT1B mRNA]PMID:27071702
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