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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69057
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr1i2
Name: nuclear receptor subfamily 1, group I, member 2
Acc ID: CHEBI:4998
Term: fenarimol
Definition: A racemate comprising equimolar amounts of (R)- and (S)-fenarimol. A sterol demethylation inhibitor, it is used as a fungicide for the treatment of blackspot, mildew and rust in tomatoes, peppers and melons, but is not approved for use within the European Union.
Chemical ID: MESH:C033789
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr1i2increases activityISORGD:691056480464CTDfenarimol results in increased activity of NR1I2 protein

PMID:16565514
Nr1i2multiple interactionsISORGD:691056480464CTDfenarimol binds to and results in increased activity of NR1I2 protein

PMID:21115097 PMID:33049310
Nr1i2multiple interactionsISORGD:691066480464CTDfenarimol binds to and results in increased activity of NR1I2 protein

PMID:21115097 PMID:33049310
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