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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735297
Species: Homo sapiens
RGD Object: Gene
Symbol: EGLN1
Name: egl-9 family hypoxia inducible factor 1
Acc ID: CHEBI:49976
Term: zinc dichloride
Definition: A compound of zinc and chloride ions in the ratio 1:2. It exists in four crystalline forms, in each of which the Zn(2+) ions are trigonal planar coordinated to four chloride ions.
Chemical ID: MESH:C016837
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
EGLN1multiple interactionsEXP 6480464CTDzinc chloride inhibits the reaction [cobaltous chloride results in increased expression of EGLN1 mRNA]; zinc chloride inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased activity of EGLN1 protein]PMID:16579968 PMID:22202117
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