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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732287
Species: Homo sapiens
RGD Object: Gene
Symbol: ATF2
Name: activating transcription factor 2
Acc ID: CHEBI:49976
Term: zinc dichloride
Definition: A compound of zinc and chloride ions in the ratio 1:2. It exists in four crystalline forms, in each of which the Zn(2+) ions are trigonal planar coordinated to four chloride ions.
Chemical ID: MESH:C016837
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ATF2multiple interactionsISOAtf2 (Mus musculus)6480464CTD[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of ATF2 protein; pyrazolanthrone inhibits the reaction [[[cupric chloride results in increased abundance of Copper] co-treated with [zinc chloride results in increased abundance of Zinc]] results in increased phosphorylation of ATF2 protein]PMID:30768131
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