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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70373
Species: Homo sapiens
RGD Object: Gene
Symbol: BAX
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:49976
Term: zinc dichloride
Definition: A compound of zinc and chloride ions in the ratio 1:2. It exists in four crystalline forms, in each of which the Zn(2+) ions are trigonal planar coordinated to four chloride ions.
Chemical ID: MESH:C016837
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BAXmultiple interactionsEXP 6480464CTD[Citric Acid co-treated with zinc chloride] results in increased expression of BAX proteinPMID:16624386
BAXmultiple interactionsISOBax (Mus musculus)6480464CTDzinc chloride promotes the reaction [Doxorubicin results in increased expression of BAX mRNA]PMID:19714248
BAXmultiple interactionsISOBax (Rattus norvegicus)6480464CTDzinc chloride affects the reaction [Cadmium Chloride results in increased expression of BAX protein]PMID:28390674
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