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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3707
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc30a2
Name: solute carrier family 30 member 2
Acc ID: CHEBI:49976
Term: zinc dichloride
Definition: A compound of zinc and chloride ions in the ratio 1:2. It exists in four crystalline forms, in each of which the Zn(2+) ions are trigonal planar coordinated to four chloride ions.
Chemical ID: MESH:C016837
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc30a2increases expressionEXP 6480464CTDzinc chloride results in increased expression of SLC30A2 mRNAPMID:20392624
Slc30a2multiple interactionsEXP 6480464CTDzinc chloride affects the reaction [Cadmium Chloride affects the expression of SLC30A2 mRNA]PMID:25653005
Slc30a2increases expressionISOSLC30A2 (Homo sapiens)6480464CTDzinc chloride results in increased expression of SLC30A2 mRNAPMID:35027733
Slc30a2multiple interactionsISOSLC30A2 (Homo sapiens)6480464CTDMTF1 protein mutant form inhibits the reaction [zinc chloride promotes the reaction [MTF1 protein binds to SLC30A2 promoter]]; NF2 protein affects the reaction [zinc chloride results in increased expression of SLC30A2 mRNA]; zinc chloride promotes the reaction [MTF1 protein binds to SLC30A2 promoter]PMID:35027733
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