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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3117
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mt1
Name: metallothionein 1
Acc ID: CHEBI:49976
Term: zinc dichloride
Definition: A compound of zinc and chloride ions in the ratio 1:2. It exists in four crystalline forms, in each of which the Zn(2+) ions are trigonal planar coordinated to four chloride ions.
Chemical ID: MESH:C016837
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mt1increases expressionEXP 6480464CTDzinc chloride results in increased expression of MT1A mRNA; zinc chloride results in increased expression of MT1A proteinPMID:17637929 PMID:8928928
Mt1multiple interactionsEXP 6480464CTDzinc chloride promotes the reaction [Glucose results in increased expression of MT1A mRNA]PMID:23056475
Mt1increases expressionISOMT1A (Homo sapiens)6480464CTDzinc chloride results in increased expression of MT1A mRNAPMID:35027733
Mt1multiple interactionsISOMT1A (Homo sapiens)6480464CTDNF2 protein affects the reaction [zinc chloride results in increased expression of MT1A mRNA]; XMU-MP-1 promotes the reaction [zinc chloride results in increased expression of MT1A mRNA]PMID:35027733
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