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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62259
Species: Mus musculus
RGD Object: Gene
Symbol: Gabrg2
Name: gamma-aminobutyric acid type A receptor, subunit gamma 2
Acc ID: CHEBI:4995
Term: felbamate
Definition: The bis(carbamate ester) of 2-phenylpropane-1,3-diol. An anticonvulsant, it is used in the treatment of epilepsy.
Chemical ID: MESH:C047360
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gabrg2multiple interactionsISOGABRG2 (Homo sapiens)6480464CTDfelbamate results in decreased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]; felbamate results in decreased activity of [GABRA4 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]; felbamate results in decreased activity of [GABRA4 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]; felbamate results in decreased activity of [GABRA6 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]; felbamate results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]; felbamate results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]; felbamate results in increased activity of [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]; felbamate results in increased activity of [GABRA2 protein binds to GABRB3 protein binds to GABRG2 protein alternative form]PMID:17056029
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