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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737544
Species: Homo sapiens
RGD Object: Gene
Symbol: LAMP1
Name: lysosomal associated membrane protein 1
Acc ID: CHEBI:49900
Term: arsenous acid
Definition: An arsenic oxoacid consisting of three hydroxy groups attached to a central arsenic atom.
Chemical ID: MESH:C032793
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
LAMP1increases expressionEXP 6480464CTDArsenic Trioxide results in increased expression of LAMP1 mRNA; Arsenic Trioxide results in increased expression of LAMP1 proteinPMID:29307831
LAMP1multiple interactionsEXP 6480464CTDAcetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of LAMP1 mRNA]; TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of LAMP1 mRNA]; TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of LAMP1 protein]PMID:29307831
LAMP1affects expressionISOLamp1 (Mus musculus)6480464CTDArsenic Trioxide affects the expression of LAMP1 proteinPMID:33462182
LAMP1increases expressionISOLamp1 (Mus musculus)6480464CTDArsenic Trioxide results in increased expression of LAMP1 mRNA; Arsenic Trioxide results in increased expression of LAMP1 proteinPMID:30237538 PMID:33462182
LAMP1multiple interactionsISOLamp1 (Mus musculus)6480464CTD3-methyladenine inhibits the reaction [Arsenic Trioxide results in increased expression of LAMP1 mRNA]; 3-methyladenine inhibits the reaction [Arsenic Trioxide results in increased expression of LAMP1 protein]; Acetylcysteine affects the reaction [Arsenic Trioxide results in increased expression of LAMP1 mRNA]; Acetylcysteine affects the reaction [Arsenic Trioxide results in increased expression of LAMP1 protein]; Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of LAMP1 protein]; TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of LAMP1 protein]PMID:30237538 PMID:33462182
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