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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736837
Species: Homo sapiens
RGD Object: Gene
Symbol: CCNF
Name: cyclin F
Acc ID: CHEBI:49900
Term: arsenous acid
Definition: An arsenic oxoacid consisting of three hydroxy groups attached to a central arsenic atom.
Chemical ID: MESH:C032793
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CCNFdecreases expressionEXP 6480464CTDArsenic Trioxide results in decreased expression of CCNF mRNA; Arsenic Trioxide results in decreased expression of CCNF proteinPMID:29159499
CCNFdecreases methylationEXP 6480464CTDArsenic Trioxide results in decreased methylation of CCNF promoterPMID:29159499
CCNFincreases expressionEXP 6480464CTDArsenic Trioxide results in increased expression of CCNF mRNAPMID:17530438
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