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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736765
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP1B1
Name: cytochrome P450 family 1 subfamily B member 1
Acc ID: CHEBI:49900
Term: arsenous acid
Definition: An arsenic oxoacid consisting of three hydroxy groups attached to a central arsenic atom.
Chemical ID: MESH:C032793
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP1B1affects expressionEXP 6480464CTDArsenic Trioxide affects the expression of CYP1B1 mRNAPMID:17530438
CYP1B1decreases expressionEXP 6480464CTDArsenic Trioxide results in decreased expression of CYP1B1 proteinPMID:29876539
CYP1B1multiple interactionsEXP 6480464CTD[Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of CYP1B1 mRNA; Resveratrol inhibits the reaction [Arsenic Trioxide results in decreased expression of CYP1B1 protein]PMID:15894607 PMID:29876539
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