Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735505
Species: Homo sapiens
RGD Object: Gene
Symbol: AQP9
Name: aquaporin 9
Acc ID: CHEBI:49900
Term: arsenous acid
Definition: An arsenic oxoacid consisting of three hydroxy groups attached to a central arsenic atom.
Chemical ID: MESH:C032793
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
AQP9affects expressionEXP 6480464CTDArsenic Trioxide affects the expression of AQP9 proteinPMID:19100828
AQP9increases expressionEXP 6480464CTDArsenic Trioxide results in increased expression of AQP9 proteinPMID:21945491
AQP9increases importEXP 6480464CTDAQP9 protein results in increased import of Arsenic TrioxidePMID:16968895
AQP9increases response to substanceEXP 6480464CTDAQP9 protein results in increased susceptibility to Arsenic TrioxidePMID:16968895
AQP9increases uptakeEXP 6480464CTDAQP9 protein results in increased uptake of Arsenic TrioxidePMID:19100828
AQP9multiple interactionsEXP 6480464CTD[Azacitidine results in increased expression of AQP9 mRNA] which results in increased uptake of Arsenic Trioxide; [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of AQP9 mRNA; [Tretinoin results in increased expression of AQP9 mRNA] which results in increased import of Arsenic Trioxide; [Tretinoin results in increased expression of AQP9 mRNA] which results in increased susceptibility to Arsenic Trioxide; AQP9 protein affects the reaction [Arsenic Trioxide promotes the reaction [Tretinoin results in decreased expression of and results in increased degradation of PIN1 protein]]; AQP9 protein affects the reaction [PIN1 protein affects the susceptibility to Arsenic Trioxide]; AQP9 protein affects the reaction [Tretinoin promotes the reaction [Arsenic Trioxide results in decreased expression of and results in increased degradation of PIN1 protein]]; AQP9 protein affects the uptake of and affects the susceptibility to Arsenic Trioxide; AQP9 protein results in increased uptake of and results in increased susceptibility to Arsenic TrioxidePMID:15336539 PMID:16968895 PMID:19225113 PMID:23563754 PMID:25953102 PMID:30093655
Go Back to source page   Continue to Ontology report