GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | NFKBIA | decreases degradation | EXP | | 6480464 | CTD | Arsenic Trioxide results in decreased degradation of NFKBIA protein | PMID:15547942 | NFKBIA | decreases expression | EXP | | 6480464 | CTD | Arsenic Trioxide results in decreased expression of NFKBIA; Arsenic Trioxide results in decreased expression of NFKBIA mRNA | PMID:12560223 PMID:15476326 PMID:20471514 | NFKBIA | decreases phosphorylation | EXP | | 6480464 | CTD | Arsenic Trioxide results in decreased phosphorylation of NFKBIA protein | PMID:11739184 PMID:30612216 | NFKBIA | increases expression | EXP | | 6480464 | CTD | Arsenic Trioxide results in increased expression of NFKBIA mRNA; Arsenic Trioxide results in increased expression of NFKBIA protein | PMID:20458559 PMID:20534739 | NFKBIA | multiple interactions | EXP | | 6480464 | CTD | [[Sulindac co-treated with Arsenic Trioxide] results in decreased phosphorylation of and results in decreased degradation of NFKBIA protein] which affects the localization of RELA protein; [Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in decreased degradation of NFKBIA protein; [BIBR 1532 co-treated with Arsenic Trioxide] affects the expression of NFKBIA mRNA; [Bortezomib co-treated with Arsenic Trioxide] affects the expression of NFKBIA protein; [Sulindac co-treated with Arsenic Trioxide] results in decreased phosphorylation of and results in decreased degradation of NFKBIA protein; Arsenic Trioxide inhibits the reaction [CXCL12 protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Arsenic Trioxide promotes the reaction [Aprepitant results in decreased phosphorylation of NFKBIA protein]; Arsenic Trioxide promotes the reaction [VS-5584 results in decreased phosphorylation of NFKBIA protein]; Arsenic Trioxide results in decreased degradation of and results in increased stability of NFKBIA protein; NFKBIA protein inhibits the reaction [Arsenic Trioxide results in increased expression of FAS protein] | PMID:12560223 PMID:15382040 PMID:16174796 PMID:18575716 PMID:18718063 PMID:25047463 PMID:29574283 PMID:30145367 PMID:32645343 | NFKBIA | multiple interactions | ISO | Nfkbia (Rattus norvegicus) | 6480464 | CTD | Arsenic Trioxide results in increased phosphorylation of and results in increased degradation of NFKBIA protein | PMID:27664319 | | ||||||||||||||||||||||
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