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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3396
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prkcb
Name: protein kinase C, beta
Acc ID: CHEBI:49900
Term: arsenous acid
Definition: An arsenic oxoacid consisting of three hydroxy groups attached to a central arsenic atom.
Chemical ID: MESH:C032793
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prkcbaffects response to substanceISOPRKCB (Homo sapiens)6480464CTDPRKCB mRNA affects the susceptibility to Arsenic TrioxidePMID:23911876
Prkcbdecreases expressionISOPRKCB (Homo sapiens)6480464CTDArsenic Trioxide results in decreased expression of PRKCB mRNAPMID:15725085
Prkcbincreases expressionISOPRKCB (Homo sapiens)6480464CTDArsenic Trioxide results in increased expression of PRKCB mRNAPMID:10673743 PMID:29442453
Prkcbmultiple interactionsISOPRKCB (Homo sapiens)6480464CTDTretinoin promotes the reaction [Arsenic Trioxide results in increased expression of PRKCB mRNA]PMID:10673743
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