GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Npm1 | affects response to substance | ISO | NPM1 (Homo sapiens) | 6480464 | CTD | NPM1 protein affects the susceptibility to Arsenic Trioxide | PMID:23877794 | Npm1 | increases expression | ISO | NPM1 (Homo sapiens) | 6480464 | CTD | Arsenic Trioxide results in increased expression of NPM1 mRNA | PMID:20458559 PMID:22521957 | Npm1 | increases response to substance | ISO | NPM1 (Homo sapiens) | 6480464 | CTD | NPM1 protein mutant form results in increased susceptibility to Arsenic Trioxide | PMID:23877794 | Npm1 | multiple interactions | ISO | NPM1 (Homo sapiens) | 6480464 | CTD | Acetylcysteine inhibits the reaction [NPM1 protein mutant form results in increased susceptibility to Arsenic Trioxide] | PMID:23877794 | |
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