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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2087
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Aldh1a1
Name: aldehyde dehydrogenase 1 family, member A1
Acc ID: CHEBI:49900
Term: arsenous acid
Definition: An arsenic oxoacid consisting of three hydroxy groups attached to a central arsenic atom.
Chemical ID: MESH:C032793
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aldh1a1decreases expressionISOAldh1a1 (Mus musculus)6480464CTDArsenic Trioxide results in decreased expression of ALDH1A1 mRNAPMID:24061648
Aldh1a1decreases expressionISOALDH1A1 (Homo sapiens)6480464CTDArsenic Trioxide results in decreased expression of ALDH1A1 mRNAPMID:29633893
Aldh1a1multiple interactionsISOALDH1A1 (Homo sapiens)6480464CTDArsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to ALDH1A1 protein]PMID:26598702
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