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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308945
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cab39l
Name: calcium binding protein 39-like
Acc ID: CHEBI:49900
Term: arsenous acid
Definition: An arsenic oxoacid consisting of three hydroxy groups attached to a central arsenic atom.
Chemical ID: MESH:C032793
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cab39ldecreases expressionISORGD:13190116480464CTDArsenic Trioxide results in decreased expression of CAB39L protein alternative form

PMID:29059232
Cab39ldecreases response to substanceISORGD:13190116480464CTDCAB39L protein alternative form results in decreased susceptibility to Arsenic Trioxide

PMID:29059232
Cab39lincreases expressionISORGD:13190116480464CTDArsenic Trioxide results in increased expression of CAB39L mRNA

PMID:27829220
Cab39lmultiple interactionsISORGD:13190116480464CTDCAB39L protein alternative form inhibits the reaction [Arsenic Trioxide results in decreased expression of CCNB1 protein], CAB39L protein alternative form inhibits the reaction [Arsenic Trioxide results in decreased expression of CCND1 protein], CAB39L protein alternative form inhibits the reaction [Arsenic Trioxide results in decreased expression of CTNNB1 mRNA], CAB39L protein alternative form inhibits the reaction [Arsenic Trioxide results in decreased expression of CTNNB1 protein], CAB39L protein alternative form inhibits the reaction [Arsenic Trioxide results in decreased expression of MYC protein]

PMID:29059232
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.