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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307189
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nfkb2
Name: nuclear factor kappa B subunit 2
Acc ID: CHEBI:49900
Term: arsenous acid
Definition: An arsenic oxoacid consisting of three hydroxy groups attached to a central arsenic atom.
Chemical ID: MESH:C032793
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfkb2decreases expressionISONFKB2 (Homo sapiens)6480464CTDArsenic Trioxide results in decreased expression of NFKB2 proteinPMID:18349030 PMID:33634982
Nfkb2increases expressionISONFKB2 (Homo sapiens)6480464CTDArsenic Trioxide results in increased expression of NFKB2 mRNAPMID:29633893
Nfkb2multiple interactionsISONFKB2 (Homo sapiens)6480464CTDArsenic Trioxide inhibits the reaction [Homoharringtonine results in increased expression of NFKB2 protein]PMID:31307525
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