GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Atf6 | decreases expression | ISO | ATF6 (Homo sapiens) | 6480464 | CTD | Arsenic Trioxide results in decreased expression of ATF6 protein | PMID:23883479 | Atf6 | increases expression | ISO | ATF6 (Homo sapiens) | 6480464 | CTD | Arsenic Trioxide results in increased expression of ATF6 mRNA; Arsenic Trioxide results in increased expression of ATF6 protein | PMID:17963750 PMID:19176121 PMID:25107562 PMID:25258189 | Atf6 | increases expression | ISO | Atf6 (Mus musculus) | 6480464 | CTD | Arsenic Trioxide results in increased expression of ATF6 mRNA | PMID:23892647 PMID:34091186 | Atf6 | increases phosphorylation | ISO | ATF6 (Homo sapiens) | 6480464 | CTD | Arsenic Trioxide results in increased phosphorylation of ATF6 protein | PMID:34560123 | Atf6 | multiple interactions | ISO | ATF6 (Homo sapiens) | 6480464 | CTD | Arsenic Trioxide promotes the reaction [nilotinib results in decreased expression of ATF6 protein]; Resveratrol inhibits the reaction [Arsenic Trioxide results in increased expression of ATF6 protein] | PMID:23883479 PMID:25107562 | Atf6 | multiple interactions | ISO | Atf6 (Mus musculus) | 6480464 | CTD | 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Arsenic Trioxide results in increased expression of and results in increased cleavage of ATF6 protein]; [Arsenic Trioxide co-treated with antimony trichloride] results in increased expression of ATF6 mRNA; [Arsenic Trioxide results in increased abundance of Reactive Oxygen Species] which results in increased expression of and results in increased cleavage of ATF6 protein; Arsenic Trioxide results in increased expression of and results in increased cleavage of ATF6 protein; Thioctic Acid inhibits the reaction [Arsenic Trioxide results in increased expression of and results in increased cleavage of ATF6 protein]; Thioctic Acid inhibits the reaction [Arsenic Trioxide results in increased expression of ATF6 mRNA] | PMID:23892647 PMID:34091186 | |
Go Back to source page | Continue to Ontology report |