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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11113
Species: Mus musculus
RGD Object: Gene
Symbol: Pklr
Name: pyruvate kinase liver and red blood cell
Acc ID: CHEBI:49900
Term: arsenous acid
Definition: An arsenic oxoacid consisting of three hydroxy groups attached to a central arsenic atom.
Chemical ID: MESH:C032793
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pklrdecreases expressionEXP 6480464CTDArsenic Trioxide results in decreased expression of PKLR mRNAPMID:30362509
Pklrmultiple interactionsEXP 6480464CTDTaurine inhibits the reaction [Arsenic Trioxide results in decreased expression of PKLR mRNA]PMID:30362509
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