GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Irf1 | decreases expression | ISO | IRF1 (Homo sapiens) | 6480464 | CTD | Arsenic Trioxide results in decreased expression of IRF1 mRNA | PMID:20458559 PMID:22521957 | Irf1 | increases expression | ISO | IRF1 (Homo sapiens) | 6480464 | CTD | Arsenic Trioxide results in increased expression of IRF1 mRNA | PMID:16914093 PMID:20953137 | Irf1 | multiple interactions | ISO | IRF1 (Homo sapiens) | 6480464 | CTD | Arsenic Trioxide promotes the reaction [[IFNG protein results in increased activity of STAT1 protein] which results in increased expression of IRF1 mRNA]; Arsenic Trioxide promotes the reaction [IFNG protein results in increased expression of IRF1 mRNA]; Arsenic Trioxide promotes the reaction [IFNG protein results in increased expression of IRF1 protein] | PMID:14668793 | |
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