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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10787
Species: Mus musculus
RGD Object: Gene
Symbol: Il17a
Name: interleukin 17A
Acc ID: CHEBI:49900
Term: arsenous acid
Definition: An arsenic oxoacid consisting of three hydroxy groups attached to a central arsenic atom.
Chemical ID: MESH:C032793
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il17adecreases expressionISOIL17A (Homo sapiens)6480464CTDArsenic Trioxide results in decreased expression of IL17A mRNA; Arsenic Trioxide results in decreased expression of IL17A proteinPMID:29950232 PMID:34108876
Il17adecreases secretionISOIL17A (Homo sapiens)6480464CTDArsenic Trioxide results in decreased secretion of IL17A proteinPMID:34108876
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