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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2153
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Arnt
Name: aryl hydrocarbon receptor nuclear translocator
Acc ID: CHEBI:49807
Term: lead(2+)
Definition: A lead cation that has formula Pb.
Chemical ID: MESH:D007854
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:7327396480464CTDLead results in increased expression of ARNT mRNA

PMID:19921347
multiple interactionsISORGD:101896480464CTDLead results in increased activity of [AHR protein binds to ARNT protein]

PMID:16093525
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.