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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1349475
Species: Homo sapiens
RGD Object: Gene
Symbol: HSPA1A
Name: heat shock protein family A (Hsp70) member 1A
Acc ID: CHEBI:4975
Term: famotidine
Definition: A guanidine that has formula C8H15N7O2S3.
Chemical ID: MESH:D015738
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HSPA1Adecreases expressionISOHspa1a (Rattus norvegicus)6480464CTDFamotidine results in decreased expression of HSPA1A proteinPMID:16945336
HSPA1Amultiple interactionsISOHspa1a (Rattus norvegicus)6480464CTDZinc Compounds analog inhibits the reaction [Famotidine results in decreased expression of HSPA1A protein]; Zinc Sulfate inhibits the reaction [Famotidine results in decreased expression of HSPA1A protein]PMID:16945336
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