GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Vegfa | decreases expression | EXP | | 6480464 | CTD | Indomethacin results in decreased expression of VEGFA protein | PMID:18431645 | Vegfa | multiple interactions | EXP | | 6480464 | CTD | [BMP7 protein co-treated with INS1 protein co-treated with Triiodothyronine co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with Indomethacin co-treated with Nicotine] affects the expression of VEGFA mRNA; allylpyrocatechol inhibits the reaction [Indomethacin results in decreased expression of VEGFA protein] | PMID:18431645 PMID:33091441 | Vegfa | decreases expression | ISO | Vegfa (Rattus norvegicus) | 6480464 | CTD | Indomethacin results in decreased expression of VEGFA mRNA; Indomethacin results in decreased expression of VEGFA mRNA alternative form | PMID:16799050 PMID:25972201 | Vegfa | decreases expression | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | Indomethacin results in decreased expression of VEGFA protein | PMID:15637740 | Vegfa | increases expression | ISO | Vegfa (Rattus norvegicus) | 6480464 | CTD | Indomethacin results in increased expression of VEGFA mRNA | PMID:16184411 PMID:17440234 | Vegfa | multiple interactions | ISO | Vegfa (Rattus norvegicus) | 6480464 | CTD | Indomethacin inhibits the reaction [Freund's Adjuvant results in increased expression of VEGFA protein]; Indomethacin promotes the reaction [morin inhibits the reaction [Freund's Adjuvant results in increased expression of VEGFA protein]]; morin promotes the reaction [Indomethacin inhibits the reaction [Freund's Adjuvant results in increased expression of VEGFA protein]] | PMID:25698669 | Vegfa | multiple interactions | ISO | VEGFA (Homo sapiens) | 6480464 | CTD | Indomethacin inhibits the reaction [VEGFA protein results in increased expression of EGR1 mRNA]; Indomethacin inhibits the reaction [VEGFA protein results in increased expression of EGR1 protein]; Indomethacin promotes the reaction [VEGFA protein results in increased expression of ACE protein] | PMID:11158990 PMID:11595463 | |
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