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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733712
Species: Homo sapiens
RGD Object: Gene
Symbol: ATF4
Name: activating transcription factor 4
Acc ID: CHEBI:49553
Term: copper(II) chloride
Definition: An inorganic chloride of copper in which the metal is in the +2 oxidation state.
Chemical ID: MESH:C029892
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ATF4multiple interactionsISOAtf4 (Rattus norvegicus)6480464CTD[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of ATF4 mRNA; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of ATF4 mRNA]PMID:20920558
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