GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Trp53 | affects expression | EXP | | 6480464 | CTD | cupric chloride affects the expression of TRP53 mRNA | PMID:23313662 | Trp53 | decreases expression | EXP | | 6480464 | CTD | cupric chloride results in decreased expression of TRP53 protein | PMID:24170445 | Trp53 | increases expression | EXP | | 6480464 | CTD | cupric chloride results in increased expression of TRP53 protein | PMID:23313662 | Trp53 | multiple interactions | ISO | TP53 (Homo sapiens) | 6480464 | CTD | [cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein; CAT protein inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]; Ethanol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]; Mannitol inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]; neocuproine inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein]; Thiourea inhibits the reaction [[cupric chloride co-treated with di(2-picolyl)amine-3(bromoacetyl)coumarin] results in increased expression of TP53 protein] | PMID:29803612 | | ||||||||||||||||||||||
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