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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731703
Species: Homo sapiens
RGD Object: Gene
Symbol: GPC2
Name: glypican 2
Acc ID: CHEBI:4953
Term: exemestane
Definition: A 17-oxo steroid that is androsta-1,4-diene-3,17-dione in which the hydrogens at position 6 are replaced by a double bond to a methylene group. A selective inhibitor of the aromatase (oestrogen synthase) system, it is used in the treatment of advanced breast cancer.
Chemical ID: MESH:C056516
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GPC2increases expressionEXP 6480464CTDexemestane results in increased expression of GPC2 mRNA

PMID:17254854
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