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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619571
Species: Mus musculus
RGD Object: Gene
Symbol: Mapk3
Name: mitogen-activated protein kinase 3
Acc ID: CHEBI:49499
Term: beryllium difluoride
Definition: The fluoride salt of beryllium (+2 oxidation state). In the solid state it exists as a glass, with four-coordinate Be(2+) tetrahedral centres and two-coordinate fluoride centres. As a gas it adopts a linear triatomic structure and in the liquid state a fluctuating tetrahedral structure. In protein crystallography it is used as a mimic of phosphate.
Chemical ID: MESH:C035982
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk3increases phosphorylationEXP 6480464CTDberyllium fluoride results in increased phosphorylation of MAPK3 proteinPMID:11867686
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