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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69157
Species: Homo sapiens
RGD Object: Gene
Symbol: BTG2
Name: BTG anti-proliferation factor 2
Acc ID: CHEBI:4911
Term: etoposide
Definition: A furonaphthodioxole that has formula C29H32O13.
Chemical ID: MESH:D005047
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BTG2increases expressionEXP 6480464CTDEtoposide results in increased expression of BTG2 mRNA; Etoposide results in increased expression of BTG2 proteinPMID:24211769 PMID:27358234
BTG2multiple interactionsEXP 6480464CTDTP53 promotes the reaction [Etoposide results in increased expression of BTG2 protein]PMID:27358234
BTG2increases expressionISOBtg2 (Mus musculus)6480464CTDEtoposide results in increased expression of BTG2 mRNAPMID:21382384 PMID:22003191
BTG2multiple interactionsISOBtg2 (Mus musculus)6480464CTDTRP53 protein affects the reaction [Etoposide results in increased expression of BTG2 mRNA]PMID:22003191
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