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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1622387
Species: Mus musculus
RGD Object: Gene
Symbol: Mapkapk2
Name: MAP kinase-activated protein kinase 2
Acc ID: CHEBI:4911
Term: etoposide
Definition: A furonaphthodioxole that has formula C29H32O13.
Chemical ID: MESH:D005047
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapkapk2increases phosphorylationEXP 6480464CTDEtoposide results in increased phosphorylation of MAPKAPK2 proteinPMID:17003255
Mapkapk2multiple interactionsEXP 6480464CTD(4-(5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl)pyridin-2-yl)-(1-phenylethyl)amine inhibits the reaction [Etoposide results in increased phosphorylation of MAPKAPK2 protein]PMID:17003255
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